Welcome to KAGB
Knowledge-Augmented Generative Biology Lab

“We develop foundational AI technologies including biological retrieval, memory, representation learning, and agentic reasoning that enable next-generation generative biology across proteins, antibodies, peptides, and precision therapeutics. We develop knowledge-augmented and agentic AI technologies for engineering next-generation biological therapeutics.” Amir Lakizadeh

Our Vision

KAGB is a next-generation research platform that integrates biological knowledge, multimodal artificial intelligence, retrieval systems, biological memory, and scientific AI agents to accelerate intelligent therapeutic discovery.

Research Themes

  • Knowledge-Augmented AI
  • Biological GraphRAG
  • Hybrid Biological Retrieval
  • Biological Memory
  • Multimodal Foundation Models
  • Scientific AI Agents
  • Generative Biology
  • Precision Therapeutics

Research Themes​

Knowledge-Augmented AI
Biological GraphRAG
Hybrid Biological Retrieval
Biological Memory
Multimodal Foundation Models
Scientific AI Agents
Generative Biology
Precision Therapeutics

Why KAGB

Transforming Biological Knowledge into Biological Intelligence

Modern AI has achieved remarkable success in biological prediction and generation. However, most current systems remain primarily data-driven and have limited ability to retrieve, integrate, and reason over the vast body of biological knowledge accumulated through decades of scientific research.

Knowledge-Augmented Generative Biology (KAGB) addresses this challenge by combining biological knowledge, multimodal artificial intelligence, retrieval systems, biological memory, and scientific AI agents into a unified research platform for intelligent therapeutic discovery.

Core Scientific Principles

Knowledge-Centric AI

Integrating biological knowledge directly into AI decision-making

Biological Memory

Preserving and reusing scientific knowledge across biological tasks

Multimodal Intelligence

Learning jointly from sequences, structures, molecular properties, and biological networks

Scientific AI Agents

Developing autonomous systems for biological reasoning and hypothesis generation

Knowledge-Guided Generation

AI-powered strategies for precision medicine and personalized

From bioinformatics to data science

Research Areas

Drug & Antibody Design

Drug & Antibody Design

AI models are used to design and optimize new antibodies and small-molecule drugs, accelerating the discovery process.

Topic

Drug Repurposing & Interactions

Machine learning helps identify new uses for existing drugs and predict harmful drug–drug interactions.

2010-2015

Polypharmacy Side Effects

We develop AI tools to detect potential adverse effects when multiple drugs are taken together.

2010-2015

Therapeutic Peptide Design

AI-driven methods are applied to design antimicrobial, antifungal, and anticancer peptides for novel therapies.

2010-2015

Identification of Cancer Driver Genes

By analyzing genomic data, our models predict cancer-related genes that play key roles in disease progression.

2010-2015

Drug Synergy

We explore combinations of drugs that work better together than individually, enabling more effective treatments.

2010-2015

Medical Diagnosis

From tumor detection to early diagnosis of autism, Alzheimer’s, and diabetic retinopathy, AI supports more accurate and faster medical decisions.

2010-2015

Some AI-based applications

Our research also covers some distinct AI-based applications such as virtual try-on, voice conversion, driver drowsiness detection, sentiment analysis, image enhancement, and deepfake detection.

Join Us

The best science doesn't happen in isolation. That's why the KAGB is designed to Inspire Collaboration. It brings together cross-functional internal Teams and allows us to work with our members on the amazing lab, creating a vibrant environment that puts science and those living with disease at the heart of everything that we do.

Dr. Lakizadeh

Head of AI Research & Principal Scientist (Pharma & Medicine)

We are eager to partner with academic researchers, students, and industry professionals to push the boundaries of AI in drug discovery and healthcare innovation.

    Join Us

    We are eager to partner with academic researchers, students, and industry professionals to push the boundaries of AI in drug discovery and healthcare innovation.